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Gastroenterology
C. difficile Diarrhea Can Be Linked to PPIs, FDA Says

The Food and Drug Administration today released a drug safety communication about proton pump inhibitors (PPIs) through its MedWatch Safety Information and Adverse Reporting Program, telling the public that Clostridium difficile–associated diarrhea can be associated with use of PPIs. The PPI... »


Gastric Cancer Subtype May Affect Bevacizumab Benefit

SAN FRANCISCO – The benefit of bevacizumab in some patients with advanced gastric cancer appears to vary by disease subtype, based on an exploratory analysis of data from the phase III AVAGAST trial. The global trial randomized 774 patients to chemotherapy plus placebo or bevacizumab (Avastin), an... »


New Risk Factor Identified for PML With Natalizumab

The Food and Drug Administration has identified a new risk factor for progressive multifocal leukoencephalopathy, a life-threatening brain infection associated with the use of natalizumab, an immunomodulatory agent used to treat multiple sclerosis and Crohn’s disease. Testing positive for... »


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